PDE-5 Inhibitors: Perfect Medications Helping Men to Deal With ED

PDE-5 Inhibitors: Perfect Medications Helping Men to Deal With ED
Manoj Kumar Published : Feb 05, 2024 Last Updated : Feb 07, 2024

Are you are searching online for information about treating erectile dysfunction?

If the answer is yes, then you must have heard about one of the famous medications called PDE-5 inhibitors. 

Although there are several drugs that are helpful in treating ED PDE-5 inhibitors medicines are highly effective. 

Erectile dysfunction is the condition when a man is not able to get and maintain the erection required for sexual intercourse. 

So, are you suffering from erectile dysfunction and want to bring back your sexual life on track?

If the answer to this question is yes then do give it a try to PDE-5 inhibitors drugs once. 

You need to know that these medications help in improving the blood flow to certain tissues. 

As a result, there is a proper flow of blood to the male reproductive organ and you start experiencing erection. 

Although these drugs were first formulated to treat cardiovascular disease but are now effective in treating ED. 

Some of the common PDE5 inhibitors available in the market include Viagra, Cialis, Levitra, and Stendra.

However, if you want to know about these medicines in detail then keep reading this blog.  

What are PDE-5 inhibitors?

PDE-5 inhibitors or phosphodiesterase type 5 inhibitors are the drugs that mainly block the actions of cGMP.

cGMP is an enzyme that is responsible for regulating the blood flow to the male reproductive organ and other body parts. 

By inhibiting PDE5, these medicines make it easy for men to get & maintain an erection. 

It is important for you to know that these drugs work only when you are sexually aroused. 

Remember these medications are not going to treat other sexual dysfunction problems such as premature ejaculation. 

How do PDE5 inhibitors work?

PDE-5 inhibitors start working by blocking the effects of the enzyme cGMP-specific phosphodiesterase type-5.

The PDE5 enzyme breaks down a cyclic nucleotide known as cyclic guanosine monophosphate.

cGMP relaxes smooth muscle tissue and regulates blood flow to parts of the body including the erectile tissue of the male reproductive organ. 

By blocking the effects of PDE5, the blood flows better in the male reproductive organ during sexual stimulation. 

As a result, it becomes easy to get and maintain an erection.

It is necessary for you to know that like other medicines, the effects of most PDE5 inhibitors are not instant. 

Depending on the medication you take, you need to wait for 15 to 60 minutes in order to get an erection. 

One of the important things to consider is that PDE5 inhibitors will not help you to get an erection randomly. 

Instead, the drugs will make it easier for you to develop and maintain an erection at the time of sexual stimulation. 

List of PDE-5 inhibitors

PDE-5 inhibitors are the first and most effective medications that come into the mind for treating ED.

Here are some common PDE-5 inhibitors:

Sildenafil (Viagra, Revatio)

Sildenafil is the common and famous PDE-5 inhibitor that is sold under the brand name Viagra.

It provides you relief from ED symptoms within an hour and works in 30 to 60 minutes. 

Not only this, but Sildenafil is also a short-acting PDE5 inhibitor. 

Tadalafil (Cialis, Adcirca)

Tadalafil is the long-acting PDE5 inhibitor that is available under the brand name Cialis. 

It is a weekend pill that shows its effects for a long time i.e., for 36 hours. 

You can easily find these drugs in the online drugstore that too at a cost-effective price. 

Avanafil (Stendra)

Available under the brand name Stendra, Avanafil is a new second-generation PDE5 inhibitor. 

This medication works just like sildenafil as well as Vardenafil, making it easy to get & maintain an erection. 

Vardenafil (Levitra)

Sold under the brand name Levitra, Vardenafil is a perfect alternative to sildenafil. 

This drug is not affected by the food which means you can take it after a meal also. 

Always remember that all these ED medications are available only on prescription. 

Make sure you take it under the supervision of the doctor to avoid any kind of side effects. 

So, treat ED right from the comfort of your home by ordering PDE-5 inhibitor medicines from a reputed online pharmacy.